Shares in Issue

Number of securities in issue

The Company’s issued share capital consists of ordinary shares with a nominal value of 10p pence each (“Ordinary Shares”), each share having equal voting rights.

The Company does not hold any Ordinary Shares in treasury and therefore the total number of Ordinary Shares with voting rights is 15,917,931. (Last updated: 3 October 2018)

Percentage of the Company’s issued share capital that is not in public hands

In accordance with the AIM Rules (Rule 26), in so far as the Company is aware, the percentage of the Company’s issued share capital that is not in public hands is 56.3%. (Last updated: 3 October 2018)

Details of any other exchanges or trading platforms

The Company is not listed on any other exchanges or trading platforms.

Details of any restrictions on the transfer of securities

There are no restrictions on the transfer of securities.

Main country of operation

England.

Country of incorporation

England and Wales.

UK City Code

Instem Plc is subject to the UK City Code on Takeovers and Mergers.

Corporate Governance Code

The Board of Instem plc is committed to the principles of good corporate governance and so far as is practicable and appropriate in view of Instem plc's size, stage of development and the nature of the Company, complies with the provisions of the QCA Code.