Pre-Close Trading Update

09 January 2012

Instem Life Science Systems plc
("Instem", the "Company" or the "Group")

Pre-Close Trading Update

Instem (AIM:INS.L), a leading provider of IT applications to the global early development healthcare market, today gives an update on trading for the year ended 31 December 2011.

Trading in the last quarter of 2011 has been mixed. The Company believes that, in its traditional area of Early Development Safety Assessment, it has won most of the contracts placed worldwide. Furthermore, BioWisdom has exceeded our expectations in the period since its acquisition in March 2011. However, as a result of conservative investment policies by contract research organisations, which had already delayed some orders from earlier in the year, some of the expected opportunities that were due for completion in December 2011 have now been delayed into 2012, with the result that revenues failed to meet our plans for the year.

As a consequence, turnover for the year is only expected to be slightly ahead of last year while profits will be materially below market expectations, although tight cost control has meant that the impact has been minimised and profit margins remain strong.

The Company’s cash position at the year end also remains strong at £3.3m (2010: £3.3m).


While the shortfall in revenues is very disappointing, the Board is encouraged by the strength of recurring revenues and the opening backlog position for 2012. There are a number of contract discussions presently ongoing, some of which had been expected to be concluded in December 2011, but should now complete in the first half of 2012. 

The Board believes that its strategies for investment in China and new products, such as Centrus, enhance the overall competitive position of the Company. As a result Provantis is expected to increase its dominance as the leading pre-clinical data management system in global pharmaceutical markets.

Acquisition Strategy

The Board continues to evaluate opportunities to acquire complementary businesses within its fragmented marketplace, seeking to capitalise on the drive by pharmaceutical companies to consolidate the number of their software suppliers, but we only intend to buy businesses on what we consider to be the right terms.

Notice of Results

Instem expects to release its preliminary statement of results for the year to 31 December 2011 on Wednesday 28 March 2012.

For further information, please contact:

Instem plc
Phil Reason, CEO +44 (0) 1785 825600
Nigel Goldsmith, CFO  
N+1 Singer (Nominated Adviser & Broker) +44 (0) 20 7496 3000
Richard Lindley  
Nick Owen  
James White  
Wallbrook Financial PR Tel: +44 (0) 20 7933 8000
Paul Cornelius or
Sam Allen  
Helen Cresswell  
Paul Whittington  

About Instem

Instem is a leading supplier of IT applications to the early development healthcare market delivering compelling solutions for data collection, management and analysis across the R&D continuum. Instem applications are in use by customers worldwide, meeting the rapidlyexpanding needs of life science and healthcare organisations for data-driven decision making leading to safer, more effective products.

Instem’s portfolio of software solutions increases client productivity by automating study-related processes while offering the unique ability to generate new knowledge through the extraction and harmonization of actionable scientific information.

Instem supports over 450 clients through full service offices in the United States, United Kingdom and China with additional locations in Japan and India.

To learn more about Instem solutions and its mission, please visit