Posting of Annual Report and Accounts

26 April 2013

Instem plc
("Instem", the "Company" or the "Group")

Posting of Annual Report and Accounts

Notice of Annual General Meeting

Instem plc (AIM: INS.L), a leading provider of IT solutions to the global early development healthcare market, announces that today it has posted to shareholders its Annual Report and Accounts for the year ended 31 December 2012, together with the Notice of the Annual General Meeting to be held at 12.00 noon on Tuesday 21 May, 2013 at the offices of Baker Tilly UK Audit LLP, 3 Hardman Street, Manchester M3 3HF.

Copies of the Annual Report and Accounts are available on Instem's website at:  http://investors.instem.com/.

For further information, please contact:

Instem plc	www.instem.com
Phil Reason, CEO	+44 (0) 1785 825600
Nigel Goldsmith, CFO
N+1 Singer (Nominated Adviser & Broker)	+44 (0) 20 7496 3000
Richard Lindley
Nick Owen
James White
Wallbrook Financial PR	Tel: +44 (0) 20 7933 8000
Paul Cornelius	or instem@walbrookpr.com
Sam Allen
Helen Cresswell
Paul Whittington

About Instem

Instem is a leading supplier of IT applications to the early development healthcare market delivering compelling solutions for data collection, management and analysis across the R&D continuum. Instem applications are in use by customers worldwide, meeting the rapidlyexpanding needs of life science and healthcare organisations for data-driven decision making leading to safer, more effective products.

Instem’s portfolio of software solutions increases client productivity by automating study-related processes while offering the unique ability to generate new knowledge through the extraction and harmonization of actionable scientific information.

Instem supports over 450 clients through full service offices in the United States, United Kingdom and China with additional locations in Japan and India.

To learn more about Instem solutions and its mission, please visit instem.com.