Director Shareholding and Other Holdings in the Company

23 December 2015

Instem plc
("Instem" or the "Company")

Director Shareholding and Other Holdings in the Company

Instem (AIM: INS), a leading provider of IT solutions to the global early development healthcare market, was notified today of the following deals in the ordinary shares of 10 pence each in the Company ("Ordinary Shares") by David Gare, Chairman.

David Gare is a trustee of the 'The DG 2008 Discretionary Settlement' (the "Trust") which on 23rd December 2015 transferred 80,000 Ordinary Shares to each of two beneficiaries, Michael Adrian Gare and Deborah Jane Walker, at a price of two hundred and thirty pence per Ordinary Share (the "Transaction").

Following the Transaction, the notifiable interests of the above parties are as follows:

  Number of Ordinary Shares Held Percentage of Total Ordinary Shares
David Gare, Chairman* 2,118,427 16.2%
Michael Adrian Gare 784,219 6.0%
Deborah Jane Walker 784,219 6.0%

*Note: these 2,118,427 Ordinary Shares are held by the Trust.

For further information, please contact:

Instem plc www.instem.com
Phil Reason, CEO +44 (0) 1785 825600
Nigel Goldsmith, CFO  
N+1 Singer (Nominated Adviser & Broker) +44 (0) 20 7496 3000
Richard Lindley  
Nick Owen  
James White  
Wallbrook Financial PR Tel: +44 (0) 20 7933 8000
Paul Cornelius or instem@walbrookpr.com
Sam Allen  
Helen Cresswell  
Paul Whittington  

About Instem

Instem is a leading supplier of IT applications to the early development healthcare market delivering compelling solutions for data collection, management and analysis across the R&D continuum. Instem applications are in use by customers worldwide, meeting the rapidlyexpanding needs of life science and healthcare organisations for data-driven decision making leading to safer, more effective products.

Instem’s portfolio of software solutions increases client productivity by automating study-related processes while offering the unique ability to generate new knowledge through the extraction and harmonization of actionable scientific information.

Instem supports over 450 clients through full service offices in the United States, United Kingdom and China with additional locations in Japan and India.

To learn more about Instem solutions and its mission, please visit instem.com.